Therefore, in this review, we summarize the expression, localization and pathophysiological role of some essential calcium channels and transporters, including the transient receptor potential channel (TRP) family, GPCR family, Purinergic receptors, SOCE channels and Mitochondrial Ca2+ transporters, which have been reported to be altered in MM (Fig. 2, Table 1). The gene discussed is P2RX7; the disease is Miyoshi myopathy.