These targets were highly enriched in Insulin resistance, PPAR signaling pathway, Adipocytokine signaling pathway, FoxO signaling pathway, Insulin signaling pathway, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Type II diabetes mellitus, cAMP signaling pathway, AMPK signaling pathway, Fc epsilon RI signaling pathway, Starch and sucrose metabolism, and so on. The gene discussed is INS; the disease is Insulin resistance.