INS and type 2 diabetes mellitus: These targets were highly enriched in Insulin resistance, PPAR signaling pathway, Adipocytokine signaling pathway, FoxO signaling pathway, Insulin signaling pathway, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Type II diabetes mellitus, cAMP signaling pathway, AMPK signaling pathway, Fc epsilon RI signaling pathway, Starch and sucrose metabolism, and so on.