Results show that many biological processes are related to diabetes, such as cellular response to lipopolysaccharide, cellular response to insulin stimulus, bile acid and bile salt transport, carbohydrate metabolic process, digestion, neutrophil chemotaxis, insulin receptor signaling pathway, negative regulation of inflammatory response, negative regulation of sequestering of triglyceride, positive regulation of fatty acid oxidation, negative regulation of cholesterol storage, glucose homeostasis, and so on. This evidence concerns the gene INSR and diabetes mellitus.