However, we observed that the anti-Ad5 antibodies levels increased slightly after 21 days of vaccination in individuals without (mean ± SD = 11.2 ± 4.8 ng/mL vs. 12.9 ± 6.4 ng/mL, p = 0.003, Figure 5D) or with prior COVID-19 (mean ± SD = 9.9 ± 2.1 ng/mL vs. 12.9 ± 1.7 ng/mL p = 0.005, Figure 5E). The gene discussed is PSEN2; the disease is COVID-19.