IL6 and Insulin resistance: For example, in a systematic review and meta-analysis, the Mediterranean diet has shown favorable effects on body composition (body weight, BMI, waist circumference), systolic and diastolic blood pressure, glycemic health (glucose, insulin, homeostatic model assessment of insulin resistance index), lipids (total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides), and inflammatory markers (C-reactive protein, interleukin-6, tumour necrosis factor-a) compared to no treatment, usual care, or different diets in adults [25].