It is noteworthy that the lasting effects of myo-inositol supplementation at physiological doses during the suckling period in adult male rats are comparable, to some extent, to those described for leptin [21] since both compounds have been shown to be capable of reversing, at least in part, the postnatal sequelae in the phenotype associated with fetal malnutrition, particularly in terms of insulin resistance. Here, LEP is linked to Insulin resistance.