NR4A1 and neoplasm: In a meta-analysis by Sun and colleagues, current drinkers had an increased risk of all hormone receptor status breast tumours compared with never drinkers, but RRs were higher for ER+PR+ tumours (RR 1.40 95% CI 1.30–1.51) and ER+PR– tumours (RR 1.39 95% CI 1.12–1.71) than ER–PR– tumours (RR 1.21 95% CI 1.02–1.43) [15].