Additionally, a study by Lopez-Chillon et al. (2019) reported that 10 weeks of consuming broccoli sprouts (30 g/day) altered body fat levels in individuals with obesity, possibly because broccoli supplement induces an alteration in indole-3-carbinol, which decreases adipogenesis by suppressing pathways of lipid accumulation mediated by PPARγ [34]. The gene discussed is PPARG; the disease is obesity due to melanocortin 4 receptor deficiency.