Combined exercise training aerobic + resistance (CARET) has recently been recommended for managing T2D; CARET may be more effective than either aerobic or resistance training alone in improving insulin resistance, inflammatory markers, glucose transporter type 4 (GLUT-4) expression (by increasing muscle mass), body weight, visceral fat mass, and lipid profiles in individuals with obesity and T2D [19,20]. This evidence concerns the gene SLC2A4 and type 2 diabetes mellitus.