Figure 2a–c shows that the Pre-Tx PGSGA score was significantly correlated to the expression levels of IL-6 in tumor specimens, and the levels of NLR, IL-6 and the percentage of MDSCs in circulation. Furthermore, by survival analyses, positive staining of IL-6 and a high Pre-Tx PGSGA score were associated with reduced OS time (Figure 2d). The gene discussed is IL6; the disease is neoplasm.