These data illustrate that largely, genes within the DUSP1 and ERK1/2 network have a negative fold change in SVGAs during JCPyV infection; however, MAPK3 (ERK1), ATF3 (ATF3), JUNB (Jun-B), and MAPK8IP1 (c-Jun-amino-terminal kinase-interacting protein 1) were differentially expressed in NHAs during viral infection (Figure 6B). The gene discussed is ATF3; the disease is viral infectious disease.