This included Caco-2 (human colorectal adenocarcinoma), E6 Vero (kidney epithelial cells from African green monkey), Huh7 (human hepatocellular carcinoma) and Huh7.5 (a subclone of Huh7 defective for the innate immune response because of a mutation in RIG-I). Here, RIGI is linked to colorectal adenocarcinoma.