In our study, higher plasma levels of the proinflammatory cytokines TNF-α, IL-6 and IL-18, and the anti-inflammatory cytokine IL-10 and the chemokines CXCL8/IL-8, CCL2/MCP-1 and CXCL10/IP-10 were found in the dengue patients compared to the healthy controls. This evidence concerns the gene CCL2 and dengue disease.