Two TLR2 SNPs (rs3804100: T > C and rs1898830: A > G) have been shown in Japanese infants to have some association with congenital CMV infection, while the TLR2 SNP (rs3804100 GG genotype) has shown a protection against intrauterine transmission of HCMV in an Israeli cohort [37]. The gene discussed is TLR2; the disease is cytomegalovirus infection.