However, OV-IL15C, expressing an IL-15 super agonist (human IL-15/IL-15Rα complex), from OV-Q1 (HSV-1 γ34.5 and ICP6 deleted; rHsvQ1) was more effective at extending survival in a CT2A syngeneic mouse GBM model than OV-Q1, and this was associated with increased in NK and T cell infiltration [27]. Here, IL15 is linked to glioblastoma.