It inhibited orthotopic bladder tumors, orthotopic breast tumors and lung metastasis, and Neuro-2A tumor growth both in injected and contralateral sites to a significantly greater extent than oHSV-1 Baco-1 (γ34.5Δ), while inducing more active tumor-specific CTL and IFNγ secretion [44,58,144]. Here, IFNG is linked to neoplasm.