Lastly, in the context of iPS11 and c-MYC or TP53R175H, this is the hitherto first indication that the repeatability of the relatively strongest drug effects upon cryopreservation can also be maintained in hiPSCs forced to overexpress cancer genes—even when the genes were introduced in an untargeted fashion using an uncontrolled lentiviral-mediated procedure. The gene discussed is MYC; the disease is cancer.