To characterize the BRD binding activity of PFI-3 to BRG1 and BRM in GBM cells, we developed a CETSA using MT330 and LN229 GBM cells transduced with either an epitope-tagged BRG1 or BRM BRD and found that PFI-3 bound well to both BRDs. The gene discussed is SMARCA2; the disease is glioblastoma.