WEE1 and neoplasm: Previously described multi-targeting (S)-3-[(3-amino-1-pyrrolidinyl)carbonyl]-4,11-dihydroxy-2-methylantra[2,3-b]furan-5,10-dione (hereinafter anthrafuran) is capable of simultaneously inhibiting topoisomerase 1 and 2, as well as protein kinases, and induces the death of tumor cells of various histogenesis [6,7].