MITF and melanoma: Docosahexaenoic acid (DHA, polyunsaturated fatty acid) was proved to reduce the proliferative and invasive potential, inhibiting the gelatinolytic activity of MMP-13, MT1-MMP, and MMP-2 in B16F10, WM115, and WM266-4 melanoma cells, by increasing the nuclear relocation of pSer675 β-catenin by a PKA-dependent pathway, while increasing MITF levels [209].