Nevertheless, little evidence indicates that USPs are also involved in the regulation of some RTKs—Table 6—namely in the regulation of EGFR (epidermal growth factor receptor), VEGFR2 (vascular endothelial growth factor receptor 2) and c-Met (also known as hepatocyte growth factor receptor—HGFR), relevant in several cancers and important therapeutic targets [157]. This evidence concerns the gene KDR and cancer.