In 2013, Yalvac et al. [19] delineated the secretome profile of TGSC-CM and identified key factors, including growth factors TGF-b1, FGF2, VEGF, and cytokines IL-5, IL-6, IL-8, and IL-10, that were attributed as the primary effectors on the cancer cells. This evidence concerns the gene FGF2 and cancer.