MPO and anti-neutrophil cytoplasmic antibody-associated vasculitis: In fact, some researchers have demonstrated that inhibition of moesin by an anti-moesin Ab is capable of inducing IFN-γ, TNF-α, and IL-6 secretion from T-cells, neutrophils, and adhesive monocytes isolated from human peripheral whole blood [69,70], and that IFN-γ and TNF-α levels are higher in the serum of patients with myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis who are positive for anti-moesin autoAb than in those who are negative for anti-moesin Ab [70].