PDE5A and type 2 diabetes mellitus: In the correlation study we involved 5 PDE5 inhibitor hit compounds, identified in a previous study [69], selected based on their 2D similarity to three seed compounds using 5 M commercial vendor libraries (IC50 < 10 μM, Table 3; the cut-off value was T2D ≥ 0.6 for the 2D similarity selection).