SFN and neoplasm: Preliminary test on normal and tumor cells showed that these complexes were effective in inhibiting cell viability and that this activity could not be uniquely ascribed to the oxidovanadium (IV) moiety: in normal cells, hTERT-HME1, and podocytes, the antiproliferative effect seemed mainly related to the vanadyl moiety, whereas the responsiveness of tumor cells HCT 116 and HT-29 seemed to be mediated by the ligands’ properties [18].