Complexes induced an increase in cell population in the G2/M phase both in non-tumor and tumor cell lines, which seemed to be correlated with the modulation of cdc2 phosphorylation; in fact, cdc2 phosphorylation in Tyr15, mediated by myt1, renders it inactive, thus blocking the progression into mitosis, and the dephosphorylation of cdc2 in this position represents a critical regulatory step for cell cycle progression [25]. This evidence concerns the gene MYT1 and neoplasm.