By performing a proteomic analysis of AR-independent prostate cancer cells (LNCaP) stimulated with IL-6 compared to normal cells, Duscharla et al. (2018) documented that VCP/p97 was overexpressed and that its IL-6-induced expression occurred through Pim-1 activation in LNCaP cells. The gene discussed is VCP; the disease is Familial prostate cancer.