Although upregulation of the expression of IFN-γ and IL-6 was observed in the salivary glands in the early phase of SS in the SATB1cKO mice, these two cytokines were not detected at 3 weeks of age (pre-SS phase) or 5 weeks of age (early SS phase) in the serum of the SATB1cKO mice (Figure 3). This evidence concerns the gene IFNG and synovial sarcoma.