Although the numbers of episodes of defecation (Figure 7d), rearings (Figure 7e), climbing (Figure 7f), and grooming (Figure 7g,h) behaviour did not show statistically significant differences between Tsc2+/+ and Tsc2+/− animals (p > 0.05), a weak but tenacious drift toward increased anxiety in Tsc2+/− mice was visible. The gene discussed is TSC2; the disease is Anxiety.