ENPP2 and COVID-19: scRNAseq analysis of BALF cells from COVID-19 patients, where macrophages predominate, indicated that ENPP2 mRNA expression was detected in different macrophage subpopulations (Figure 4C/UMAP, S3C/UMAP), pending FACS validation, where it could modulate their maturation in an autocrine mode via LPA [79,80,81].