SETBP1 and cytomegalovirus infection: In the current study, we have expanded our results to elderly individuals, as we have been able to recruit both CMV-seronegative and seropositive elderly individuals to assess for the first time the effects of age and CMV infection on T-cells, using Staphylococcal enterotoxins, such as SEB, which are the most potent known T-cell mitogens [29,30], to probe the functionality of T-cell subsets.