PPARG and metabolic dysfunction-associated steatotic liver disease: We compared this model with two other models of NAFLD: the obese and diabetic ob/ob mice and the lipodystrophic Adipoq-Cretg/+;Ppargfl/fl mice (hereafter called PpargFΔ/Δ), in which Pparg is deleted in preadipocytes but is present in the rest of the body [16].