CUX2 and metabolic dysfunction-associated steatotic liver disease: Interestingly, the sex-biased expression profile of a panel of these sex-biased genes, including Cux2, Acot3, Fmo3 and Hsd3b5, was similarly dampened in the two other models of NAFLD previously used in this study, namely the ob/ob and PpargFΔ/Δ mice (Figure 3C,D).