IL4 and allergic asthma: We extracted total RNA from the lung tissue of mice from both the control and the F2-administered groups in the allergic asthma model and examined the changes in the Th2 cytokines IL-4, IL-5, and IL-13, eosinophil-recruiting chemokine CCL11 [19] and allergic asthma-related cytokine IL-33 [20] using RT-qPCR (Figure 4A).