The expression of 24 genes (BCL11B, DOCK5, PLEC, SRPK2, TNFSF10, ELAVL2, YWHAQ, GNA12, HIST2H2BF, SLC43A2, TMEM184B, STRIP2, PDK1, OLR1, NAV1, MKI67, SLC25A37, OSBPL3, HES6, ABCA1, ACOT9, NKD1, APP, and SLC16A3) was upregulated in the HNSCC tissues (n = 518) compared with normal tissues (n = 44) (Figure S2A,B). This evidence concerns the gene HES6 and head and neck squamous cell carcinoma.