The expression of 24 genes (BCL11B, DOCK5, PLEC, SRPK2, TNFSF10, ELAVL2, YWHAQ, GNA12, HIST2H2BF, SLC43A2, TMEM184B, STRIP2, PDK1, OLR1, NAV1, MKI67, SLC25A37, OSBPL3, HES6, ABCA1, ACOT9, NKD1, APP, and SLC16A3) was upregulated in the HNSCC tissues (n = 518) compared with normal tissues (n = 44) (Figure S2A,B). The gene discussed is PDK1; the disease is head and neck squamous cell carcinoma.