Lambert et al. (2011) reported the hypermethylation of RASSF1A, GSTP1, CHRNA3, and DOK1 in HCC tumors, and they also claimed that alcohol intake was related to hypomethylation of MGMT and hypermethylation of GSTP1 associated with HBV infection [68]. Here, RASSF1 is linked to hepatocellular carcinoma.