Recently, a review by Cai and Jeong (2020) [240] highlighted that defects in mitophagy have been widely associated with PD (especially in the PINK1/Parkin pathway but also in others like lipid-mediated mitophagy) and that increased rates of mtDNA deletions have been observed in PD patients, which could be related to dysfunctions in this process of mitochondrial quality control. The gene discussed is PINK1; the disease is Parkinson disease.