When both these markers were evaluated together, CRC patients who coexpressed KIF11 (IRS) at high level and KIF14 at low level had markedly shorter OS than those with the opposite expression pattern (400 days vs. 1696 days; p = 0.01; Figure 3D); a similar relationship was found when PS was used to measure KIF11 expression (459 days vs. not reached; p = 0.01; Figure 3E). This evidence concerns the gene KIF14 and colorectal carcinoma.