However, when PS (cut-point = 2.3) instead of IRS was taken as a measure of KIF11 expression, the same analysis demonstrated that CRC patients with KIF11 overexpression (n = 23) had markedly shorter OS time than those with KIF11 underexpression (459 days vs. 1637 days, p = 0.02; Figure 3B). Here, IARS1 is linked to colorectal carcinoma.