MCAM and melanoma: CMCs express a variety of surface antigens used in various isolation and detection techniques, including melanoma cell markers, e.g., MCAM (melanoma cell adhesion molecule, MCAM/MUC18/CD146) [25], MART-1 (melanoma antigen recognized by T cells 1/Melan-A) [29], MAGE-A3 (melanoma antigen A3), PAX3 (paired box 3), HMW-MAA (human high-molecular weight melanoma-associated antigen) [30] and GM2/GD2 (gangliosides) [31].