In humans, Sirt1-AS LncRNA suppressed the miRNA-induced translational repression of Sirt1 mRNA by masking the miR-29c binding site on the Sirt1 3′ untranslated region and promoting the proliferation of the human hepatocellular carcinoma (HCC) cell lines [40]. This evidence concerns the gene SIRT1 and hepatocellular carcinoma.