KRAS and cancer: Interactions with the spike protein were strongest for simeprevir (a direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4; DrugBank), euphol (tetracyclic triterpene alcohol; the main constituent of the sap of the medicinal plant Euphorbia tirucalli, with anti-cancer activity) and ZINC252515584 [41,48].