Fabry disease (FD, OMIM #301500) is an X-linked inherited metabolic disease (IMD) due to lysosomal α-galactosidase A activity deficiency (GalA-EC 3.2.1.22), which has a key role in the glycosphingolipid degradation pathway, leading to cellular dysfunction and microvascular pathology [1]. Here, GLA is linked to Fabry disease.