Several reports also demonstrated the role of the SYK gene as a potential prognostic marker in various cancer types, such as human breast carcinomas, cervical carcinogenesis [55], human lung cancer [56], ovarian cancer, and neck cancer, glioblastoma, etc. It is recommended that the abnormal expression level of the SYK gene is associated with CRC development. The gene discussed is SYK; the disease is lung cancer.