Inherited disease-causative impairments of the low-density lipoprotein-receptor gene, (LDLR) present in 70–90% of subjects, and, less commonly, the apolipoprotein B gene (APOB), as well as proprotein convertase subtilin/Kexin, member nine genes (PCSK9) have been linked to raised lipoprotein cholesterol in FH (190–400 mg/dL) [3]. The gene discussed is PCSK9; the disease is familial hyperaldosteronism.