BCL2 and cancer: In order to deliver multiple drugs to cancer cells simultaneously, Ding et al. (2020) generated an ultra pH-sensitive nanoparticle based on polyethylene glycol-poly(diisopropylamino)ethyl methacrylate (PEG-PDPA), with doxorubicin encapsulated in the hydrophilic cavity and a BCL-2 inhibitor navitoclax encapsulated in the hydrophobic membrane.