Among analyzed clinicopathological factors, a high Child–Pugh cirrhosis score (B/C) and high AJCC TNM stage (IIIA/IIIB/IIIC/IVA/IVB) had a significantly negative impact on RFS (Table 3); conversely, high serum albumin level showed a significantly positive impact on RFS (Table 3) and was associated with better RFS than low serum albumin level was (median RFS, 19.0 vs. 6.0 months, p value = 0.0233) (Figure 1B). This evidence concerns the gene ALB and Cirrhosis.