Clinical and laboratory indicators related to renal outcome, such as serum creatinine, eGFR, and proteinuria, for patients with all glomerular diseases included age, hypertension, systolic blood pressure, diastolic blood pressure, Hb, HbA1c, BUN, ESR, hs-CRP, ferritin, total protein, albumin, ferritin, C3, C4, IgG, and IgE (Supplementary Table S1). The gene discussed is C3; the disease is glomerular disorder.