IGHE and infection: IgE is usually related to protection against parasites [4], but its role in other infections is not usually considered, despite there being studies that have demonstrated the presence of specific IgE antibodies against viruses such as H1N1 influenza [30], respiratory syncytial [31], HIV1 [32], varicella [33], parvovirusB19 [34], and rhinovirus (RV) [35].