Unlike what was observed here for the Snail1 and Snail2 mRNAs, a previous study reported that both Snail1 and Snail2 proteins were not detectable in immunohistochemistry (IHC) experiments performed on normal human thyroid tissues or cell lines but expressed at very high levels in human thyroid carcinoma tissues and ATC-derived cell lines [50]. The gene discussed is SNAI2; the disease is thyroid gland carcinoma.