BDNF (p = 0.09), proBDNF (p = 0.69), mBDNF (p = 0.09), rBDNF (p = 0.44), MIF (p = 0.4), and SCF (p = 0.64) concentration did not differ between subgroups of depression without and with diagnosis change. Here, BDNF is linked to depressive disorder.