Significant differences were found in the levels of CCL18 (p = 0.001), CCL22 (p = 0.03), and CCL4 (p = 0.02) when we compared MD, migraine, and controls; however, no differences were found in IL-1β or CCL18 levels of MD vs. migraine patients (Figure 5). The gene discussed is CCL4; the disease is Menkes disease.