Therefore, we measured the levels of IL-1β, CCL3, CCL4, CXCL1, CCL22, and CCL18 in a cohort of 83 patients with MD, which included 44 EOMD and 39 LOMD, and 64 patients with migraine without vestibular symptoms to control the effect of migraine itself on cytokine levels. This evidence concerns the gene IL1B and Menkes disease.