Preoperative serum TSH [1.564 (0.95–2.90) vs. 1.05 (0.85–1.70)], TSH receptor Ab [10.5 (6.5–16.25) vs. 5 (5–8)] and Anti-TPO Ab [4573 (1563–9405) vs. 28 (17.5–28)] levels are significantly higher in the autoimmune thyroiditis group than the goiter group. This evidence concerns the gene TSHR and goiter.