Moreover, the findings have demonstrated that glioma secretes MCP-1 to induce the infiltration of microglia/macrophages [1,46,47,50], in this study, the massive amount of MCP-1+/Iba1− cells might serve as a chemokine-producing source for the recruitment of Iba1+ microglia/macrophages in glioma. Here, AIF1 is linked to glioma.