Depletion or knock-out of PRMT6 reduced (i) the cell proliferation and clonogenic capacity of the breast cancer cells [169], (ii) the cell migration and invasiveness of prostate cancer cells [172], (iii) endometrial cancer cell proliferation and migration [173], (iv) proliferation of lung adenocarcinoma cells [176] and (v) tumorigenic properties of gastric cancer cells [180]. This evidence concerns the gene PRMT6 and lung adenocarcinoma.