Thus, a carriage for the T2D-associated alleles of GSS and GGT7 is related to the expression level of MYH7B, PROCR, and EDEM2 in the pancreas as well as with the levels of MYH7B, PROCR, EDEM2, MAP1LC3A, GGT7, NFS1, PIGU, NCOA6, TRPC4AP and ACSS2 in insulin-sensitive tissues. The gene discussed is INS; the disease is type 2 diabetes mellitus.