Eighteen low- and high-risk genotype combinations were found to be significantly associated with type 2 diabetes and two genotype combinations such as GGT7 rs6119534-C/T × GSS rs1801310-A/A GGT7 and rs6119534-C/T × GSS rs13041792-G/G showed the strongest protective effects against disease risk. Here, GGT7 is linked to type 2 diabetes mellitus.